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[糖尿病患者中Fc IgG片段的粒细胞受体及补体C3成分的行为]

[Behavior of granulocytic receptors for Fc IgG fragment and C3 component of complement in patients with diabetes].

作者信息

Jabłońska E, Pietruska Z

机构信息

Zakład Immunopatologii AM w Białymstoku.

出版信息

Endokrynol Pol. 1991;42(3):455-62.

PMID:1364495
Abstract

The count of peripheral neutrophils having the superficial receptors for Fc IgG fragment (FcR) and C3 component of the complement (CR) was determined in diabetic patients by using the rosette tests EA and EAC according to the modified Buescher method. A significantly lower percentage of neutrophils with FcR and CR receptors was found in patients with both insulin-dependent and noninsulin-dependent diabetes. The lowest values were found in noncompensated diabetes; in compensated diabetes they were higher but still significantly lower than in the controls. The difference was significant in both tests used. The results obtained suggest that the observed fall in the percentage of neutrophils with FcR and CR receptors is caused by metabolic disturbances associated with diabetes.

摘要

采用改良的比舍尔方法,通过EA和EAC玫瑰花结试验,测定糖尿病患者外周血中具有Fc IgG片段(FcR)和补体C3成分(CR)表面受体的中性粒细胞计数。在胰岛素依赖型和非胰岛素依赖型糖尿病患者中,发现具有FcR和CR受体的中性粒细胞百分比显著降低。在未代偿性糖尿病患者中该值最低;在代偿性糖尿病患者中该值较高,但仍显著低于对照组。在两种所用试验中差异均显著。所得结果表明,观察到的具有FcR和CR受体的中性粒细胞百分比下降是由与糖尿病相关的代谢紊乱引起的。

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[Behavior of granulocytic receptors for Fc IgG fragment and C3 component of complement in patients with diabetes].[糖尿病患者中Fc IgG片段的粒细胞受体及补体C3成分的行为]
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