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The removal of cartilage matrix in vivo by papain; prevention of recovery with cortisone, hydrocortisone and prednisoione by a direct action on cartilage.

作者信息

McCLUSKEY R T, THOMAS L

出版信息

Am J Pathol. 1959 Jul-Aug;35(4):819-33.

PMID:13670314
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1934832/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/ccf6d1ea1572/amjpathol00576-0123-g.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/097b1817ce85/amjpathol00576-0121-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/2444048bc17d/amjpathol00576-0121-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/2eb8bc3d8e90/amjpathol00576-0121-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/04a9eee72606/amjpathol00576-0121-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/4b11b3391bb8/amjpathol00576-0121-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/39dbda9cd0f2/amjpathol00576-0121-f.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/6e995c3fcd64/amjpathol00576-0121-g.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/ecec181922dc/amjpathol00576-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/2929abbc5a99/amjpathol00576-0123-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/e9136de68238/amjpathol00576-0123-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/e2b6d17cbc6f/amjpathol00576-0123-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/6cd1953432dc/amjpathol00576-0123-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/ce11371fcbd2/amjpathol00576-0123-f.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/ccf6d1ea1572/amjpathol00576-0123-g.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/097b1817ce85/amjpathol00576-0121-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/2444048bc17d/amjpathol00576-0121-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/2eb8bc3d8e90/amjpathol00576-0121-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/04a9eee72606/amjpathol00576-0121-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/4b11b3391bb8/amjpathol00576-0121-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/39dbda9cd0f2/amjpathol00576-0121-f.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/6e995c3fcd64/amjpathol00576-0121-g.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/ecec181922dc/amjpathol00576-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/2929abbc5a99/amjpathol00576-0123-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/e9136de68238/amjpathol00576-0123-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/e2b6d17cbc6f/amjpathol00576-0123-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/6cd1953432dc/amjpathol00576-0123-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/ce11371fcbd2/amjpathol00576-0123-f.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e304/1934832/ccf6d1ea1572/amjpathol00576-0123-g.jpg

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The removal of cartilage matrix in vivo by papain; prevention of recovery with cortisone, hydrocortisone and prednisoione by a direct action on cartilage.木瓜蛋白酶在体内对软骨基质的去除；可的松、氢化可的松和泼尼松龙通过对软骨的直接作用来防止恢复。
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Biophys J. 1964 Jan;4(1 Pt 2):SUPPL 215-37. doi: 10.1016/s0006-3495(64)86940-x.
2
THE EFFECTS OF PAPAIN, VITAMIN A, AND CORTISONE ON CARTILAGE MATRIX IN VIVO.木瓜蛋白酶、维生素A和可的松对体内软骨基质的作用
Biophys J. 1964 Jan;4(1 Pt 2):SUPPL207-13. doi: 10.1016/s0006-3495(64)86939-3.
3
SERUM PROTEINS AND GLYCOPROTEINS IN PAPAIN-INJECTED RABBITS.木瓜蛋白酶注射兔子体内后的血清蛋白质和糖蛋白

本文引用的文献

1
Effect of cortisone on growing bones of the rat.可的松对大鼠生长中骨骼的影响。
Proc Soc Exp Biol Med. 1951 Apr;76(4):722-4. doi: 10.3181/00379727-76-18607.
2
Radioautographic visualization of sulfur-35 disposition in the articular cartilage and bone of suckling rats following injection of labeled sodium sulfate.注射标记的硫酸钠后，对乳鼠关节软骨和骨骼中硫-35分布的放射自显影观察。
J Exp Med. 1951 May;93(5):451-8. doi: 10.1084/jem.93.5.451.
3
The removal of cartilage matrix, in vivo, by papain; identification of crystalline papain protease as the cause of the phenomenon.
Am J Pathol. 1963 Sep;43(3):419-35.
4
Relapsing polychondritis. Report of two necropsied cases with histochemical investigation of the cartilage lesion.复发性多软骨炎。两例尸检病例报告及软骨病变的组织化学研究。
Am J Pathol. 1963 Mar;42(3):251-69.
5
Prevention by cortisone of the changes in cartilage induced by an excess of vitamin A in rabbits.可的松对过量维生素A所致家兔软骨变化的预防作用
Am J Pathol. 1963 Mar;42(3):271-83.
6
Effect of cortisone on the epiphysial cartilage. A histologic and autoradiographic study.
Virchows Arch Pathol Anat Physiol Klin Med. 1963;336:209-19. doi: 10.1007/BF00957910.
7
Comparison of the effects of papain n vitamin A on cartilage. I. The effects in rabbits.木瓜蛋白酶和维生素A对软骨影响的比较。I. 对兔子的影响。
J Exp Med. 1960 May 1;111(5):705-18. doi: 10.1084/jem.111.5.705.
8
Increased fixation of sulfur-35 by cartilage in vitro following depletion of the matrix by intravenous papain.静脉注射木瓜蛋白酶使基质耗尽后，体外软骨对硫-35的固定增加。
J Exp Med. 1960 Nov 1;112(5):743-50. doi: 10.1084/jem.112.5.743.
9
The early penetration of experimental gastric ulcers in ra s receiving cortisone.接受可的松的大鼠实验性胃溃疡的早期穿透情况
Am J Pathol. 1961 Jan;38(1):73-87.
10
Effect of intra-articular corticosteroid injections on primate cartilage.关节内注射皮质类固醇对灵长类动物软骨的影响。
Ann Rheum Dis. 1977 Feb;36(1):74-9. doi: 10.1136/ard.36.1.74.
木瓜蛋白酶在体内对软骨基质的去除；确定结晶木瓜蛋白酶是该现象的原因。
J Exp Med. 1958 Sep 1;108(3):371-84. doi: 10.1084/jem.108.3.371.
4
Cartilage changes in papain-treated rabbits.木瓜蛋白酶处理的兔子的软骨变化。
Am J Pathol. 1957 Nov-Dec;33(6):1237-45.
5
The metabolism of mucopolysaccharides in animals: the effect of cortisone and hydrocortisone on rat skin.动物体内黏多糖的代谢：可的松和氢化可的松对大鼠皮肤的影响。
Endocrinology. 1957 Mar;60(3):376-81. doi: 10.1210/endo-60-3-376.
6
Reversible collapse of rabbit ears after intravenous papain, and prevention of recovery by cortisone.静脉注射木瓜蛋白酶后兔耳的可逆性塌陷，以及可的松对恢复的预防作用。
J Exp Med. 1956 Aug 1;104(2):245-52. doi: 10.1084/jem.104.2.245.
7
The metabolism of mucopolysaccharides in animals. III. Further studies on skin utilizing C14-glucose, C14-acetate, and S35-sodium sulfate.动物体内粘多糖的代谢。III. 利用C14-葡萄糖、C14-乙酸盐和S35-硫酸钠对皮肤进行的进一步研究。
J Biol Chem. 1956 Jan;218(1):139-45.
8
Effect of cortisone and other steroids upon in vitro synthesis of chondroitin sulfate.
Proc Soc Exp Biol Med. 1954 Jul;86(3):558-61. doi: 10.3181/00379727-86-21164.