Anastasiadis Aristotelis G, Davis Anne R, Sawczuk Ihor S, Fleming Megan, Perelman Michael A, Burchardt Martin, Shabsigh Ridwan
Department of Urology, College of Physicians and Surgeons of Columbia University, 161 Fort Washington Avenue, Herbert Irving Pavilion, New York, NY 10032, USA.
Support Care Cancer. 2003 Nov;11(11):700-6. doi: 10.1007/s00520-003-0484-2. Epub 2003 Sep 13.
We investigated quality of life aspects, including health-related quality of life, psychological functioning, relationship issues and sexual functioning in kidney cancer patients.
We conducted an anonymous, cross-sectional survey of a random sample of patients with kidney cancer from a national database. A questionnaire was mailed to 301 members of the Kidney Cancer Association. The questionnaire included demographics, medical history, the Watts Sexual Function Questionnaire (WSFQ), the SF-12 Health Survey, the Center for Epidemiologic Studies Depression Scale (CES-D), and the Revised Dyadic Adjustment Scale (RDAS).
Of the 266 eligible participants, 84 (33%) returned the questionnaire. The mean ages of the respondents were 57.5 and 57.9 years for men and women, respectively. Overall, the total WSFQ scores as well as the four domain scores (desire, arousal, orgasm and satisfaction) were similar in men and women, and lower than in female breast cancer and male hypertensive populations reported in the literature, indicating relatively worse sexual function. While subjects reported health-related quality of life and relationship scores similar to the general population, 51% of men and 57% of women reported depressive symptoms (CES-D >/=16).
This is the first study in which sexual function in patients with renal cancer has been addressed. While most patients remain sexually active in non-distressed relationships, many reported depressive symptoms, and sexual functioning may be worse than in comparable chronically ill populations. Quality of life and sexual function issues should be addressed when counseling urological cancer patients.
我们调查了肾癌患者生活质量的各个方面，包括与健康相关的生活质量、心理功能、人际关系问题和性功能。
我们对来自全国数据库的随机抽取的肾癌患者样本进行了匿名横断面调查。向肾癌协会的301名成员邮寄了调查问卷。问卷包括人口统计学信息、病史、瓦茨性功能问卷（WSFQ）、SF - 12健康调查、流行病学研究中心抑郁量表（CES - D）以及修订的二元调适量表（RDAS）。
在266名符合条件的参与者中，84名（33%）回复了问卷。男性和女性受访者的平均年龄分别为57.5岁和57.9岁。总体而言，男性和女性的WSFQ总分以及四个领域得分（欲望、唤起、性高潮和满意度）相似，且低于文献报道的女性乳腺癌患者和男性高血压患者群体，表明性功能相对较差。虽然受试者报告的与健康相关的生活质量和人际关系得分与普通人群相似，但51%的男性和57%的女性报告有抑郁症状（CES - D≥16）。
这是第一项研究肾癌患者性功能的研究。虽然大多数患者在关系融洽时仍保持性活跃，但许多人报告有抑郁症状，且性功能可能比类似的慢性病患者群体更差。在为泌尿系统癌症患者提供咨询时，应解决生活质量和性功能问题。
