Kanaya N, Takehisa S, Nicoloff H, Nikolova T, Damianova V
Department of Biology, Keio University, Yokohama, Japan.
Mutat Res. 1992 Jan;281(1):47-54. doi: 10.1016/0165-7992(92)90035-g.
Effects of extracts from Vicia faba were compared with those of Zea mays for the induction of sister-chromatid exchanges (SCEs) and of chromosome aberrations (CAs) in Chinese hamster ovary (CHO) cells. CA induction by the maize extract was also tested in human lymphocytes. The extracts from roots and leaves of Vicia faba induced CAs and SCEs in CHO cells. The extracts from maize leaves also induced SCEs and CAs in CHO cells, and CAs in human lymphocytes. Maize extracts were more potent in inducing SCEs than Vicia extracts and the SCE- and CA-inducing capacity of maize extracts decreased during preincubation before addition to cells.
比较了蚕豆提取物与玉米提取物对中国仓鼠卵巢（CHO）细胞中姐妹染色单体交换（SCE）和染色体畸变（CA）的诱导作用。还在人淋巴细胞中测试了玉米提取物对CA的诱导作用。蚕豆根和叶的提取物在CHO细胞中诱导了CA和SCE。玉米叶提取物也在CHO细胞中诱导了SCE和CA，并在人淋巴细胞中诱导了CA。玉米提取物诱导SCE的能力比蚕豆提取物更强，并且在添加到细胞之前的预孵育过程中，玉米提取物诱导SCE和CA的能力下降。
