血清脂肪酶：诊断急性酒精性胰腺炎的更佳检测方法。

Serum lipase: a better test to diagnose acute alcoholic pancreatitis.

作者信息

Gumaste V, Dave P, Sereny G

机构信息

Department of Medicine, Mount Sinai Services-City Hospital Center at Elmhurst, Elmhurst, New York 11373.

出版信息

Am J Med. 1992 Mar;92(3):239-42. doi: 10.1016/0002-9343(92)90070-r.

DOI:10.1016/0002-9343(92)90070-r

PMID:1372152

Abstract

OBJECTIVE

To determine whether serum lipase is a better test than serum amylase to diagnose acute alcoholic pancreatitis.

PATIENTS

Two hundred two asymptomatic chronic alcoholics (Group A) and 29 patients with image-proven pancreatitis (Group P).

MEASUREMENTS

Serum lipase was measured using the Kodak Ektachem clinical chemistry slide. Serum amylase was estimated using the Kodak Ektachem clinical chemistry slide or the Beckman Astra amylase chemistry module.

RESULTS

The level of serum amylase in Group A ranged from 17 to 347 U/L (mean 71, SD +/- 36 U/L) and in Group P from 180 to 2,985 U/L (mean 722, SD +/- 663 U/L). Thirteen of 29 patients (45%) with image-proven pancreatitis had levels that overlapped those found in asymptomatic alcoholics. The serum lipase levels in Group A ranged from 34 to 600 U/L (mean 186, SD +/- 111 U/L), while in Group P, the corresponding figures were 1,011 to 25,706 U/L (mean 5,822, SD +/- 5,664 U/L). None of the 29 patients with image-proven pancreatitis had levels that overlapped those found in asymptomatic alcoholics.

CONCLUSIONS

Serum lipase is a better test that serum amylase to diagnose acute alcoholic pancreatitis.

摘要

目的

确定血清脂肪酶在诊断急性酒精性胰腺炎方面是否比血清淀粉酶是更好的检测方法。

患者

202名无症状慢性酒精中毒者（A组）和29名经影像学证实患有胰腺炎的患者（P组）。

测量

使用柯达Ektachem临床化学玻片测量血清脂肪酶。使用柯达Ektachem临床化学玻片或贝克曼Astra淀粉酶化学模块估算血清淀粉酶。

结果

A组血清淀粉酶水平为17至347 U/L（平均71，标准差±36 U/L），P组为180至2985 U/L（平均722，标准差±663 U/L）。29名经影像学证实患有胰腺炎的患者中有13名（45%）其水平与无症状酒精中毒者的水平重叠。A组血清脂肪酶水平为34至600 U/L（平均186，标准差±111 U/L），而在P组中，相应数字为1011至25706 U/L（平均5822，标准差±5664 U/L）。29名经影像学证实患有胰腺炎的患者中没有一人的水平与无症状酒精中毒者的水平重叠。