Awogi T, Murata K, Uejima M, Kuwahara T, Asanami S, Shimono K, Morita T
Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan.
Mutat Res. 1992 Feb-Mar;278(2-3):181-5. doi: 10.1016/0165-1218(92)90231-n.
Micronucleus tests of potassium bromate (KBrO3) and potassium chromate (K2CrO4) were conducted with peripheral blood reticulocytes (PB-RETs) of CD-1 male mice dose intraperitoneally. Peripheral blood cells collected from the tail were stained supravitally with acridine orange (AO) using AO-coated glass slides. Both KBrO3 and K2CrO4 induced micronuclei in PB-RETs in the same manner as in polychromatic erythrocytes of bone marrow.
用CD-1雄性小鼠的外周血网织红细胞(PB-RETs)进行腹腔注射溴酸钾(KBrO3)和铬酸钾(K2CrO4)的微核试验。从尾部采集的外周血细胞用吖啶橙(AO)包被的载玻片进行活体染色。KBrO3和K2CrO4均以与骨髓多染红细胞相同的方式诱导PB-RETs中的微核形成。