Farm-grade chlorpyrifos (Durmet) is genotoxic in somatic and germ-line cells of Drosophila. - Suppr | 超能文献

Farm-grade chlorpyrifos (Durmet) is genotoxic in somatic and germ-line cells of Drosophila.

作者信息

Patnaik K K, Tripathy N K

机构信息

Department of Zoology, Berhampur University, India.

出版信息

Mutat Res. 1992 May 1;279(1):15-20. doi: 10.1016/0165-1218(92)90261-w.

DOI:10.1016/0165-1218(92)90261-w

Abstract

The mutagenic potential of Durmet, a farm-grade formulation of chlorpyrifos, was studied in the Drosophila wing mosaic and sex-linked recessive lethal tests. Larvae of the 2nd or 3rd instar carrying suitable recessive genetic markers on chromosome 3 were exposed to different concentrations of the insecticide and the frequency of induction of mutant mosaic spots on the wings was noted. The Basc technique was followed to study the induction of sex-linked recessive lethals. On the basis of the frequency of induction of mosaic wing spots and sex-linked recessive lethals, it is concluded that Durmet is genotoxic in somatic cells as well as germ cells of Drosophila.

摘要

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