Hogg N
Imperial Cancer Research Fund, London, UK.
Immunol Today. 1992 Apr;13(4):113-5. doi: 10.1016/0167-5699(92)90103-E.
The rapid advances being made in unravelling the biochemistry and function of the three categories of adhesion molecule involved in leucocyte-endothelial-cell interactions, namely selectins, integrins and the Ig super-family molecules, were highlighted at a recent meeting. In this short report, Nancy Hogg describes these developments and the prospects for anti-adhesion molecule therapy in the clinic.
最近的一次会议强调了在揭示参与白细胞-内皮细胞相互作用的三类粘附分子(即选择素、整合素和免疫球蛋白超家族分子)的生物化学和功能方面取得的快速进展。在这份简短的报告中,南希·霍格描述了这些进展以及抗粘附分子疗法在临床上的前景。