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1
Observations on the pyrogenic response and its application to the bioassay of endotoxin.关于热原反应的观察及其在内毒素生物测定中的应用。
J Clin Invest. 1961 Feb;40(2):295-301. doi: 10.1172/JCI104256.
2
The role of endotoxin during typhoid fever and tularemia in man. IV. The integrity of the endotoxin tolerance mechanisms during infection.内毒素在人类伤寒热和兔热病中的作用。IV. 感染期间内毒素耐受机制的完整性。
J Clin Invest. 1969 Apr;48(4):613-29. doi: 10.1172/JCI106020.
3
Bioassay of endotoxin: correlation between pyrogenicity for rabbits and lethality for chick embryos.内毒素的生物测定：家兔致热原性与鸡胚致死性之间的相关性。
J Infect Dis. 1966 Dec;116(5):529-36. doi: 10.1093/infdis/116.5.529.
4
Use of a bioassay for endotoxin in clinical infections and in experimental vasomotor collapse.生物测定法在内毒素临床感染及实验性血管舒缩性虚脱中的应用。
Antimicrob Agents Chemother (Bethesda). 1967;7:132-6.
5
A moderate dose of cycloheximide does not prevent the febrile response to endotoxin but interfere with induction of pyrogenic tolerance in rabbit.中等剂量的放线菌酮不会阻止对内毒素的发热反应，但会干扰兔子内热原耐受性的诱导。
J Physiol Pharmacol. 1992 Jun;43(2):165-71.
6
Susceptibility rhythm to E. coli endotoxin and bioassay.对大肠杆菌内毒素的易感性节律及生物测定
Proc Soc Exp Biol Med. 1960 Jan;103:142-4. doi: 10.3181/00379727-103-25439.
7
Biological activities of tritiated endotoxins: correlation of the Limulus lysate assay with rabbit pyrogen and complement-activation assays for endotoxin.氚标记内毒素的生物学活性：鲎试剂检测法与兔热源检测法及内毒素补体激活检测法的相关性
J Lab Clin Med. 1977 Feb;89(2):308-15.
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Evaluation of the applicability of the bacterial endotoxin test to antibiotic products.细菌内毒素检测应用于抗生素产品的适用性评估。
Biologicals. 2000 Sep;28(3):155-67. doi: 10.1006/biol.2000.0251.
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Characterization of an endotoxin-like substance recovered from an intravenous antibiotic solution involving pyrogenic reactions.从涉及热原反应的静脉用抗生素溶液中回收的一种类内毒素物质的特性分析。
Prog Clin Biol Res. 1979;29:465-71.
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Assessment of pyrogenic response of lipoteichoic acid by the monocyte activation test and the rabbit pyrogen test.通过单核细胞活化试验和家兔热原试验评估脂磷壁酸的热原反应。
Regul Toxicol Pharmacol. 2015 Oct;73(1):356-60. doi: 10.1016/j.yrtph.2015.07.025. Epub 2015 Jul 30.

引用本文的文献

1
ENDOTOXIN TOLERANCE. II. ITS OCCURRENCE IN PATIENTS WITH PYELONEPHRITIS.内毒素耐受性。II. 其在肾盂肾炎患者中的发生情况。
J Clin Invest. 1963 May;42(5):618-25. doi: 10.1172/JCI104752.
2
ENDOTOXIN TOLERANCE. I. ITS INDUCTION BY EXPERIMENTAL PYELONEPHRITIS.内毒素耐受性。一、实验性肾盂肾炎对其的诱导作用。
J Clin Invest. 1963 May;42(5):610-7. doi: 10.1172/JCI104751.
3
Symposium on bacterial endotoxins. I. Relationship of chemical composition to biological activity.细菌内毒素研讨会。I. 化学成分与生物活性的关系。
Bacteriol Rev. 1961 Dec;25(4):427-36. doi: 10.1128/br.25.4.427-436.1961.
4
Quantitative studies of human leukocytic and febrile response to single and repeated doses of purified bacterial endotoxin.对单次及重复剂量纯化细菌内毒素的人体白细胞和发热反应的定量研究。
J Clin Invest. 1962 Jan;41(1):162-72. doi: 10.1172/JCI104459.
5
RELATIONSHIP BETWEEN PARTICLE SIZE AND BIOLOGICAL ACTIVITY OF E. COLI BOIVIN ENDOTOXIN.大肠杆菌博伊文内毒素的颗粒大小与生物活性之间的关系
J Clin Invest. 1965 Apr;44(4):592-602. doi: 10.1172/JCI105172.
6
SOME CYTOLOGICAL AND PATHOGENIC PROPERTIES OF SPHEROPLASTS OF CANDIDA ALBICANS.白色念珠菌原生质体的一些细胞学和致病特性
J Bacteriol. 1964 Sep;88(3):795-801. doi: 10.1128/jb.88.3.795-801.1964.
7
CHARACTERIZATION OF THE PYROGENICITY OF CANDIDA ALBICANS, SACCHAROMYCES CEREVISIAE, AND CRYPTOCOCCUS NEOFORMANS.白色念珠菌、酿酒酵母和新型隐球菌的致热特性
J Bacteriol. 1964 Sep;88(3):660-6. doi: 10.1128/jb.88.3.660-666.1964.
8
MECHANISMS OF ENDOTOXIN TOLERANCE. II. RELATIONSHIP BETWEEN ENDOTOXIN TOLERANCE AND RETICULOENDOTHELIAL SYSTEM PHAGOCYTIC ACTIVITY IN MAN.内毒素耐受性的机制。II. 内毒素耐受性与人体网状内皮系统吞噬活性之间的关系。
J Exp Med. 1964 Feb 1;119(2):241-64. doi: 10.1084/jem.119.2.241.
9
RELATIONSHIP OF BODY TEMPERATURE TO THE LETHAL ACTION OF BACTERIAL ENDOTOXIN.体温与细菌内毒素致死作用的关系
J Clin Invest. 1964 Feb;43(2):151-69. doi: 10.1172/JCI104899.
10
Studies on the pathogenesis of fever. XI. Quantitative features of the febrile response to leucocytic pyrogen.发热发病机制的研究。十一、对白细胞致热原发热反应的定量特征
J Exp Med. 1963 Mar 1;117(3):349-64. doi: 10.1084/jem.117.3.349.

本文引用的文献

1
Studies on the pathogenesis of fever. I. The presence of transferable pyrogen in the blood stream following the injection of typhoid vaccine.发热发病机制的研究。I. 注射伤寒疫苗后血流中可转移热原的存在。
J Exp Med. 1955 May 1;101(5):519-28. doi: 10.1084/jem.101.5.519.
2
Bacterial pyrogens.细菌热原质
Pharmacol Rev. 1957 Dec;9(4):427-79.
3
Pathogenesis of fever: evidence for direct cerebral action of bacterial endotoxins.发热的发病机制：细菌内毒素直接作用于大脑的证据。
Trans Assoc Am Physicians. 1957;70:64-73.
4
Studies on the pathogenesis of fever. IV. The site of action of leucocytic and circulating endogenous pyrogen.发热发病机制的研究。IV. 白细胞源性和循环内源性致热原的作用部位。
J Exp Med. 1958 Feb 1;107(2):291-303. doi: 10.1084/jem.107.2.291.
5
Studies on the pathogenesis of fever. IX. Characteristics of endogenous serum pyrogen and mechanisms governing its release.发热发病机制的研究。IX. 内源性血清热原的特性及其释放的调控机制。
J Exp Med. 1957 Dec 1;106(6):787-809. doi: 10.1084/jem.106.6.787.
6
Measurement of the human febrile response to a bacterial pyrogen.人体对细菌热原发热反应的测量。
Clin Sci. 1956 Nov;15(4):485-9.
7
Studies on the pathogenesis of fever. II. Identification of an endogenous pyrogen in the blood stream following the injection of typhoid vaccine.发热发病机制的研究。II. 注射伤寒疫苗后血流中内源性致热原的鉴定。
J Exp Med. 1955 Nov 1;102(5):499-516. doi: 10.1084/jem.102.5.499.
8
Fractionation studies on the tumor-necrotizing agent from Serratia marcescens (Shear's polysaccharide).粘质沙雷氏菌（希尔多糖）肿瘤坏死因子的分级分离研究
J Natl Cancer Inst. 1954 Apr;14(5):1099-108.
9
Rabbit responses to human threshold doses of a bacterial pyrogen.兔子对人类细菌热原阈值剂量的反应。
J Pharm Pharmacol. 1954 May;6(5):325-32. doi: 10.1111/j.2042-7158.1954.tb10954.x.
10
Studies on the pathogenesis of fever. II. Characterization of fever-producing substances from polymorphonuclear leukocytes and from the fluid of sterile exudates.发热的发病机制研究。II. 多形核白细胞及无菌性渗出液中致热物质的特性
J Exp Med. 1953 Nov;98(5):493-508. doi: 10.1084/jem.98.5.493.

Observations on the pyrogenic response and its application to the bioassay of endotoxin.

作者信息

KEENE W R, SILBERMAN H R, LANDY M

出版信息

J Clin Invest. 1961 Feb;40(2):295-301. doi: 10.1172/JCI104256.

DOI:10.1172/JCI104256
PMID:13752168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC290722/
Abstract
摘要