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Effect of spectinomycin on peptide chain initiation.

作者信息

Reusser F

出版信息

J Antibiot (Tokyo). 1976 Dec;29(12):1328-33. doi: 10.7164/antibiotics.29.1328.

DOI:10.7164/antibiotics.29.1328
PMID:137888
Abstract

Spectinomycin inhibits the formation and causes dissociation of performed specific cell-free initiation complexes prepared with the trinucleotide A-U-G or R17 phage RNA, fmet-RNAF and either 30S ribosomal subunits or 70S ribosomes. Both the initiation factor and the Mg2+-induced processes are subject to inhibition by spectinomycin. The only exception is the Mg2+-induced 70S initiation system formed with A-U-G which is stimulated by spectinomycin.

摘要

相似文献

1
Effect of spectinomycin on peptide chain initiation.
J Antibiot (Tokyo). 1976 Dec;29(12):1328-33. doi: 10.7164/antibiotics.29.1328.
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Initial rate kinetic analysis of the mechanism of initiation complex formation and the role of initiation factor IF-3.起始复合物形成机制及起始因子IF-3作用的初始速率动力学分析
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