Yokochi T, Fukada M, Kawai M, Zhang Y H, Jiang G Z, Takahashi K
Department of Microbiology, Aichi Medical University School of Medicine, Japan.
Infect Immun. 1992 Nov;60(11):4953-6. doi: 10.1128/iai.60.11.4953-4956.1992.
The adjuvant action of various lipopolysaccharides on immune responses to syngeneic tissue extract in mice was examined. Only lipopolysaccharides possessing the linear mannose homopolysaccharides as O-specific polysaccharides exhibited definite adjuvant action on immune responses to the autoantigens. The intensity of this adjuvant activity of lipopolysaccharide from Klebsiella O3 seemed to be the strongest.
研究了各种脂多糖对小鼠同基因组织提取物免疫反应的佐剂作用。只有以线性甘露糖同多糖作为O-特异性多糖的脂多糖对自身抗原的免疫反应表现出明确的佐剂作用。来自肺炎克雷伯菌O3的脂多糖的这种佐剂活性强度似乎最强。