Kobayashi S, Fujishiro N, Sugiyama K
Department of Internal Medicine, Meijo-Hospital, Nagoya, Japan.
Intern Med. 1992 Jun;31(6):778-81. doi: 10.2169/internalmedicine.31.778.
A 32-year-old female was diagnosed as having systemic lupus erythematosus based on her laboratory tests. In 1985 she began to complain of hearing difficulty. Her hearing ability deteriorated to the extent that her audiogram revealed a hearing loss of 90 db to 110 db in both ears in September 1989. She received two series of plasmapheresis treatments using the double filtration method. After two series of plasmapheresis treatments, her hearing improved dramatically. This improvement suggests that circulating immune complexes and anti-phospholipid antibodies might play a pathological role in the hearing impairment in SLE patient.
一名32岁女性经实验室检查被诊断为患有系统性红斑狼疮。1985年，她开始抱怨听力困难。到1989年9月，她的听力严重下降，听力图显示双耳听力损失90分贝至110分贝。她接受了两次使用双重过滤法的血浆置换治疗。经过两次血浆置换治疗后，她的听力显著改善。这一改善表明循环免疫复合物和抗磷脂抗体可能在系统性红斑狼疮患者的听力损害中起病理作用。
