Hara T, Nagata M, Mizuno Y, Ura Y, Matsuo M, Ueda K
Department of Pediatrics, Faculty of Medicine, Kyushu University, Saga, Japan.
Acta Paediatr. 1992 Jun-Jul;81(6-7):547-9. doi: 10.1111/j.1651-2227.1992.tb12292.x.
Immunological evaluations were performed in 59 children with at least five episodes of parotid swelling. Autoantibody(ies) was transiently or persistently detected in 12 (20%) of 59 patients with recurrent parotitis. Three of the 12 children with autoantibodies were diagnosed as having Sjögren's syndrome. The mean age at onset of parotid swelling in Sjögren's syndrome was significantly higher than that of recurrent parotitis of unknown etiology. The present study and the review of the literature suggest that patients with the onset of parotid swelling at age five years or over deserve screening for underlying systemic immune disorders.
对59例至少有5次腮腺肿胀发作的儿童进行了免疫学评估。在59例复发性腮腺炎患者中，有12例（20%）短暂或持续检测到自身抗体。12例有自身抗体的儿童中有3例被诊断为干燥综合征。干燥综合征患者腮腺肿胀发作的平均年龄显著高于病因不明的复发性腮腺炎患者。本研究及文献综述表明，5岁及以上出现腮腺肿胀的患者值得筛查潜在的全身性免疫疾病。
