Rosenbusch B, Sterzik K, Lauritzen C
Abteilung Frauenheilkunde und Geburtshilfe, Universität Ulm.
Geburtshilfe Frauenheilkd. 1992 Aug;52(8):479-82. doi: 10.1055/s-2007-1023793.
Constituents of the follicular fluid (FF) have been suspected to influence fertilizability and cytogenetic constitution of human oocytes. Therefore, we analysed the FF concentrations of 17 beta-estradiol (E2), progesterone (P), testosterone (T), and prolactin (PRL) of 114 oocytes recovered for in vitro fertilisation (IVF). 46 of these oocytes were fertilised and transferred to the maternal uterus. Among the unfertilized gametes, 27 were not analysable. 30 were normal haploid, and 11 were classified as abnormal. There was no significant difference between fertilised and unfertilized oocytes for FF concentrations of E2, P, T, and PRL and for the E2/P ratios. Similarly, we detected no significant difference between normal and abnormal oocytes for these parameters.
卵泡液（FF）的成分被怀疑会影响人类卵母细胞的受精能力和细胞遗传学构成。因此，我们分析了为体外受精（IVF）回收的114个卵母细胞的卵泡液中17β-雌二醇（E2）、孕酮（P）、睾酮（T）和催乳素（PRL）的浓度。其中46个卵母细胞受精并移植到母体子宫。在未受精的配子中，27个无法进行分析。30个为正常单倍体，11个被归类为异常。受精和未受精的卵母细胞在E2、P、T和PRL的卵泡液浓度以及E2/P比值方面没有显著差异。同样，我们在这些参数上未检测到正常和异常卵母细胞之间存在显著差异。
