耐壮观霉素淋病奈瑟菌
Spectinomycin-resistant Neisseria gonorrhoeae.
作者信息
Thornsberry C, Jaffee H, Brown S T, Edwards T, Biddle J W, Thompson S E
出版信息
JAMA. 1977 May 30;237(22):2405-6.
PMID:140251
Abstract
Neisseria gonorrhoeae resistant to high levels of spectinomycin (more than 2,048 microng/ml), were isolated from specimens obtained from a patient with urethritis. The bacterial resistance to spectinomycin is probably due to ribosomal changes that are a result of a chromosomal mutation. If spectinomycin fails to cure gonorrhea, spectinomycin resistance should be considered.
摘要
从一名尿道炎患者的标本中分离出了对高剂量壮观霉素（超过2048微克/毫升）耐药的淋病奈瑟菌。细菌对壮观霉素的耐药性可能是由于染色体突变导致核糖体发生变化所致。如果壮观霉素无法治愈淋病，则应考虑壮观霉素耐药性。
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