Grennan D M, Ghobarey A F, Hadidi T, El-Badawey S, Hamid H A, Dick W C, Buchanan W W
Scott Med J. 1977 Apr;22(2):139-45. doi: 10.1177/003693307702200210.
The clinical features of 78 patients with SLE seen in Cairo and Glasgow are reviewed. Raynaud's phenomenon was recorded more frequently here than in previous series. The value of serial measurements of anti-DNA antibodies, C3 and C4 in the management of SLE is discussed. Although antibodies to native DNA paralleled the disease course in only a minority of SLE patients anti-DNA antibodies were present during all major SLE exacerbations and could be diagnostically useful. Serious systemic infections complicating the management of SLE patients could occur and their diagnosis is discussed.
对在开罗和格拉斯哥就诊的78例系统性红斑狼疮（SLE）患者的临床特征进行了回顾。与之前的系列研究相比，这里记录到的雷诺现象更为常见。讨论了抗DNA抗体、C3和C4的系列测量在SLE治疗中的价值。虽然仅少数SLE患者中天然DNA抗体与疾病病程平行，但在所有主要的SLE病情加重期间均存在抗DNA抗体，且具有诊断意义。SLE患者治疗过程中可能会出现严重的全身感染，并对其诊断进行了讨论。
