Magyar E, Talerman A, Mohácsy J, Wouters H W, de Bruijn W C
Virchows Arch A Pathol Anat Histol. 1977 Apr 6;373(3):267-78. doi: 10.1007/BF00432241.
Muscle changes were studied in biopsy material obtained from 100 patients suffering from classical rheumatoid arthritis. The abnormalities consisted of denervation atrophy of type II muscle fibres, degenerative changes in the sarcoplasm including presence of nemaline rods, and changes within the interstitium: namely perivascular nodular myositis, lymphocytic accumulations, different stages of vasculitis and abnormalities within the intramuscular nerves and muscle spindles. The muscles examined were always severely affected. It is considered that the simultaneous presence of these abnormalities is suggestive of rheumatoid arthritis. The importance of histochemical studies is emphasized. The literature concerning muscle changes in rheumatoid arthritis is reviewed.
对100例典型类风湿性关节炎患者的活检材料进行了肌肉变化研究。异常表现包括Ⅱ型肌纤维失神经萎缩、肌浆的退行性改变，包括出现棒状小体，以及间质内的变化：即血管周围结节性肌炎、淋巴细胞聚集、不同阶段的血管炎以及肌内神经和肌梭内的异常。所检查的肌肉总是受到严重影响。认为这些异常同时存在提示类风湿性关节炎。强调了组织化学研究的重要性。回顾了有关类风湿性关节炎肌肉变化的文献。
