DUNCAN L E, BUCK K, LYNCH A
Science. 1963 Nov 15;142(3594):972-3. doi: 10.1126/science.142.3594.972.
Low-density (1.019 to 1.063) lipoprotein labeled with radioiodine enters the inner layer of the canine aortic wall directly from the aortic lumen. Its rate of entry is greatest in the proximal aorta and decreases progressively down the length of the aorta. A similar gradient was observed previously for the accumulation of cholesterol early in experimental atherosclerosis.
用放射性碘标记的低密度(1.019至1.063)脂蛋白直接从主动脉腔进入犬主动脉壁的内层。其进入速率在主动脉近端最大,并沿主动脉长度逐渐降低。先前在实验性动脉粥样硬化早期胆固醇的积聚中也观察到类似的梯度。