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[从正常犬和烧伤犬血液中分离出的中分子量肽对小鼠组织蛋白水解的影响]

[Effect of middle molecular weight peptides, isolated from blood of intact dogs and those with burns, on proteolysis in mouse tissue].

作者信息

Val'dman B M, Pushkarev V P, Skobeleva N A, Lifshits R I

出版信息

Vopr Med Khim. 1992 May-Jun;38(3):60-2.

PMID:1413655
Abstract

The median molecular-weight peptides (MMP), detected in blood of patients with burns and in that of experimental animals with burns, were shown to affect various systems in vivo. The MMP from the blood of intact dogs and of the animals with burns exhibited the modifying effect on proteolysis within acid and neutral pH ranges in liver and brain tissues of mouse. The MMP appears to be involved in the regulation of proteolysis both in normal state and in burns.

摘要

在烧伤患者血液以及烧伤实验动物血液中检测到的中位分子量肽(MMP),已被证明在体内会影响各种系统。来自正常犬类和烧伤动物血液中的MMP,对小鼠肝脏和脑组织在酸性及中性pH范围内的蛋白水解具有调节作用。MMP似乎在正常状态和烧伤状态下都参与了蛋白水解的调节。

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