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通过短暂、强烈的经皮躯体刺激实现疼痛的长期缓解。

Prolonged relief of pain by brief, intense transcutaneous somatic stimulation.

作者信息

Melzack Ronald

机构信息

Department of Psychology, McGill University, Montreal, Que., Canada.

出版信息

Pain. 1975 Dec;1(4):357-373. doi: 10.1016/0304-3959(75)90073-1.

Abstract

The purpose of this study was to examine the effects of brief, intense transcutaneous electrical stimulations at trigger points or acupuncture points on severe clinical pain. The McGill Pain Questionnaire was used to measure the change in pain quality and intensity produced by stimulation. The data indicate that the procedure provides a powerful method for the control of some forms of severe pathological pain. The average pain decrease during stimulation sessions was 75% for pain due to peripheral nerve injury, 66% for phantom limb pain, 62% for shoulder-arm pain, and 60% for low-back pain. The duration of relief frequently outlasted the period of stimulation by several hours, occasionally for days or weeks. Different patterns of the amount and duration of pain relief were observed. Daily stimulation carried out at home by the patient sometimes provided gradually increasing relief over periods of weeks or months. Control experiments, which included two forms of placebo stimulation, showed that brief, intense electrical stimulation is significantly more effective than placebo contributions. Possible neural mechanisms that underlie these patterns of pain relief by brief, intense stimulation are discussed.

摘要

本研究的目的是检验在触发点或穴位进行短暂、强烈的经皮电刺激对严重临床疼痛的影响。使用麦吉尔疼痛问卷来测量刺激产生的疼痛性质和强度的变化。数据表明,该方法为控制某些形式的严重病理性疼痛提供了一种有力手段。在刺激过程中,因周围神经损伤引起的疼痛平均减轻75%,幻肢痛减轻66%,肩臂痛减轻62%,腰痛减轻60%。缓解期常常比刺激期持续数小时,偶尔持续数天或数周。观察到了疼痛缓解量和持续时间的不同模式。患者在家中进行的每日刺激有时会在数周或数月内逐渐增加缓解程度。包括两种形式的安慰剂刺激在内的对照实验表明,短暂、强烈的电刺激比安慰剂更有效。文中讨论了短暂、强烈刺激缓解疼痛这些模式背后可能的神经机制。

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