Debuse P J
Paediatric Intensive Care Unit, Royal Children's Hospital, Brisbane, Australia.
Acta Paediatr. 1992 Sep;81(9):723-4. doi: 10.1111/j.1651-2227.1992.tb12346.x.
The classical form of thiamine deficiency in children is comprised of peripheral neuropathy, encephalopathy and high-output cardiac failure, predominantly right-sided. "Shoshin beriberi" cardiac failure has a different presentation, with vasoconstriction, hypotension and severe metabolic acidosis. A three-month breast-fed infant developed these features (biochemical tests confirmed the diagnosis). His mother, although non-symptomatic, had biochemical evidence of thiamine deficiency.
儿童硫胺素缺乏的经典形式包括周围神经病变、脑病和高输出量心力衰竭，主要为右侧心力衰竭。“干性脚气病”心力衰竭有不同的表现，包括血管收缩、低血压和严重代谢性酸中毒。一名三个月大的母乳喂养婴儿出现了这些症状（生化检查确诊）。他的母亲虽然没有症状，但有硫胺素缺乏的生化证据。
