哇巴因促进儿茶酚胺释放的作用。
The action of ouabain in promoting the release of catecholamines.
作者信息
Duncan C J
出版信息
Experientia. 1977 Jul 15;33(7):923-4. doi: 10.1007/BF01951283.
PMID:142645
Abstract
It is suggested that ouabain promotes catecholamine release by causing a rise in intracellular Na+ which, in turn, causes an elevated steady-state level of intracellular Ca2+. It is suggested that the Na+-K+-ATPase is not directly involved in exocytosis at either adrenergic or cholinergic synapses.
摘要
有观点认为，哇巴因通过使细胞内钠离子浓度升高来促进儿茶酚胺释放，而细胞内钠离子浓度升高反过来又会导致细胞内钙离子稳态水平升高。还有观点认为，钠钾ATP酶在肾上腺素能或胆碱能突触的胞吐作用中并不直接起作用。
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