Miyashita Y, Morimoto S, Fukuo K, Imanaka S, Koh E, Tamatani M, Ogihara T
Department of Geriatric Medicine, Osaka University Medical School, Japan.
Gerontology. 1992;38(5):258-67. doi: 10.1159/000213338.
The cholesteryl ester transfer activity (CETA) is a measurement of the transfer of cholesteryl ester from HDL to VLDL, LDL or peripheral cells. Its role in the development of early coronary heart disease is not clear. In the present study, serum levels of CETA, lipoprotein(a) [Lp(a)] and other lipid-related factors were compared in 10 normal young subjects, 28 healthy elderly subjects and 14 normolipemic elderly patients with angina pectoris. Compared to the young normals and healthy elderly subjects, the elderly patients with angina pectoris showed significantly decreased mean serum CETA levels, and significantly increased mean serum levels of Lp(a) and apoprotein B. These results may indicate that decreased serum values of CETA participate in the development of angina pectoris in normolipemic elderly patients.
胆固醇酯转移活性（CETA）是对胆固醇酯从高密度脂蛋白（HDL）转移至极低密度脂蛋白（VLDL）、低密度脂蛋白（LDL）或外周细胞的一种测量。其在早期冠心病发展中的作用尚不清楚。在本研究中，对10名正常年轻受试者、28名健康老年受试者和14名血脂正常的老年心绞痛患者的血清CETA水平、脂蛋白（a）[Lp（a）]及其他脂质相关因子进行了比较。与年轻正常受试者和健康老年受试者相比，老年心绞痛患者的平均血清CETA水平显著降低，而平均血清Lp（a）水平和载脂蛋白B显著升高。这些结果可能表明，血清CETA值降低参与了血脂正常的老年患者心绞痛的发生发展。
