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沙特阿拉伯2型糖尿病中血缘关系与家族聚集性之间的潜在协同作用。

Suspected synergism between consanguinity and familial aggregation in type 2 diabetes mellitus in Saudi Arabia.

作者信息

Anokute C C

机构信息

College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

出版信息

J R Soc Health. 1992 Aug;112(4):167-9. doi: 10.1177/146642409211200403.

DOI:10.1177/146642409211200403
PMID:1433147
Abstract

A retrospective study of 210 cases of diabetes was carried out at King Khalid University Hospital diabetes clinic to delineate etiologic factors in non-insulin dependent diabetes mellitus (NIDDM). Standardised detailed questionnaires were administered to both cases and controls and the information sought included general demographics, dietary patterns, anthropometric values, family history, consanguinity and familial aggregation of Diabetes Mellitus (DM). Familial aggregation yielded an odds ratio of 6:2 which suggests a causal association with DM. A synergistic effect of familial aggregation was observed which needs to be further explored in future studies.

摘要

在哈利德国王大学医院糖尿病诊所对210例糖尿病患者进行了一项回顾性研究,以确定非胰岛素依赖型糖尿病(NIDDM)的病因。对病例组和对照组均采用标准化的详细问卷进行调查,所收集的信息包括一般人口统计学资料、饮食模式、人体测量值、家族史、近亲结婚情况以及糖尿病(DM)的家族聚集性。家族聚集性得出的优势比为6:2,这表明与糖尿病存在因果关联。观察到家族聚集性的协同效应,这需要在未来的研究中进一步探讨。

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