Booth M, Bundy D A
Wellcome Trust Research Centre for Parasitic Infections, Department of Biology, Imperial College of Science, Technology and Medicine, London.
Parasitology. 1992 Aug;105 ( Pt 1):151-7. doi: 10.1017/s0031182000073807.
Programmes to control Ascaris lumbricoides, Trichuris trichiura and hookworm infections have often been targeted at each infection separately, but the advent of benign and broad-spectrum anthelmintics suggests that combined control may be feasible. The extent to which the infections co-occur in communities will determine the need for, and potential benefits of, such a combined approach. This paper examines the comparative distribution of the three geohelminths in different geographical areas and shows that A. lumbricoides and T. trichiura have closely related distributions, while hookworm infection is largely independent of the other two. These results indicate that many communities are at risk of disease from infection by more than one species of helminth. The similar distributions and epidemiological characteristics of A. lumbricoides and T. trichiura suggest that simultaneous control of these two parasites by the same strategy would be feasible and highly beneficial to communities. Multiple species control strategies which aim to control hookworm infection may require a more complicated protocol with more precise locality targeting.
控制蛔虫、鞭虫和钩虫感染的项目通常分别针对每种感染，但良性和广谱驱虫药的出现表明联合控制可能是可行的。这些感染在社区中的共现程度将决定这种联合方法的必要性和潜在益处。本文研究了三种土源性蠕虫在不同地理区域的比较分布，结果表明蛔虫和鞭虫的分布密切相关，而钩虫感染在很大程度上独立于其他两种。这些结果表明，许多社区面临着感染不止一种蠕虫而患病的风险。蛔虫和鞭虫相似的分布和流行病学特征表明，通过相同策略同时控制这两种寄生虫是可行的，并且对社区非常有益。旨在控制钩虫感染的多物种控制策略可能需要更复杂的方案和更精确的地区针对性。
