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采用反相高效液相色谱法测定牛蒡子中牛蒡苷及牛蒡子苷元的含量。

Determination of arctiin and arctigenin in Fructus Arctii by reverse-phase HPLC.

作者信息

Sun W J, Sha Z F, Gao H

机构信息

Shaanxi Provincial Institute for Drug Control, Xian.

出版信息

Yao Xue Xue Bao. 1992;27(7):549-51.

PMID:1442089
Abstract

The fruits of Arctium lappa L. is an often-used herbal drug in traditional Chinese medicine for the treatment of common cold caused by wind and heat. This drug contained many constituents, principally arctiin, with arctigenin in smaller amount. In this work, arctiin has been isolated from the fruits of Arctium lappa, and then enzymolyzed into arctigenin. The obtained arctiin and arctigenin were characterized and then used as standards for their determination in the crude drug by HPLC. The method is simple, rapid and accurate.

摘要

牛蒡果实是中药中常用于治疗风热感冒的草药。该药物含有多种成分,主要是牛蒡子苷,牛蒡子素含量较少。在本研究中,从牛蒡果实中分离出牛蒡子苷,然后将其酶解为牛蒡子素。对得到的牛蒡子苷和牛蒡子素进行了表征,并用作通过高效液相色谱法测定生药中它们的标准品。该方法简便、快速、准确。

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