Hinton R, Jinnah R H, Johnson C, Warden K, Clarke H J
Johns Hopkins Hospital, Baltimore, Maryland.
Am J Sports Med. 1992 Sep-Oct;20(5):607-12. doi: 10.1177/036354659202000521.
This study compares the basic mechanical properties of two groups of commercially available fascia lata allografts processed by different means (solvent-dehydrated and sterilized via gamma radiation, and freeze-dried without secondary sterilization). The results reveal significantly (P less than 0.05) higher stiffness, higher maximum load to failure, and higher maximum load per unit width of graft with the solvent-dried as opposed to the freeze-dried fascia lata. Subsections of individual solvent-dried specimens were also more uniform in their mechanical properties than those of the freeze-dried allografts.
Fascia lata is used as a graft material in a variety of orthopaedic procedures. Allograft fascia lata offers an increased cross-sectional area of material and eliminates the morbidity associated with the harvesting of autologous tissues. However, the structural uniformity of such large grafts has been questioned. Processing techniques used in the sterilization and storage of such grafts is varied and represents a potential source of variation in the mechanical properties of allograft specimens. The results of this study suggest that a commercially available solvent-dehydrated form of fascia lata provides a more suitable grafting material than freeze-dried specimens obtained from tissue banks.
本研究比较了两组通过不同方式处理的市售阔筋膜同种异体移植物的基本力学性能（溶剂脱水并经伽马射线灭菌，以及冻干且无二次灭菌）。结果显示，与冻干阔筋膜相比，溶剂干燥的阔筋膜在刚度、最大破坏载荷以及单位宽度的最大载荷方面均显著更高（P小于0.05）。单个溶剂干燥标本的各部分在力学性能上也比冻干同种异体移植物更加均匀。
阔筋膜在多种骨科手术中用作移植材料。同种异体阔筋膜提供了更大的材料横截面积，并消除了与自体组织采集相关的发病率。然而，这种大型移植物的结构均匀性受到了质疑。此类移植物在灭菌和储存中使用的处理技术各不相同，这是同种异体移植物标本力学性能潜在的变异来源。本研究结果表明，市售的溶剂脱水形式的阔筋膜比从组织库获得的冻干标本提供了更合适的移植材料。
