大疱性类天疱疮疱液中免疫反应性白细胞介素-5水平升高。 - Suppr

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超能文献

Increased immunoreactive interleukin-5 levels in blister fluids of bullous pemphigoid.

作者信息

Endo H, Iwamoto I, Fujita M, Okamoto S, Yoshida S

机构信息

Department of Dermatology, Chiba University School of Medicine, Japan.

出版信息

Arch Dermatol Res. 1992;284(5):312-4. doi: 10.1007/BF00372588.

DOI:10.1007/BF00372588

PMID:1444583

Abstract

摘要

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Increased immunoreactive interleukin-5 levels in blister fluids of bullous pemphigoid.大疱性类天疱疮疱液中免疫反应性白细胞介素-5水平升高。

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The existence of a platelet-activating factor (Paf-acether)-like substance in blister fluid derived from patients with bullous pemphigoid as demonstrated by human platelet aggregation techniques.采用人血小板聚集技术证实，大疱性类天疱疮患者水疱液中存在一种血小板活化因子（Paf-乙酰醚）样物质。

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Elevated levels of interleukin-8 in blister fluid of bullous pemphigoid compared with suction blisters of healthy control subjects.与健康对照受试者的抽吸水疱相比，大疱性类天疱疮疱液中白细胞介素-8水平升高。

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Elevated levels of eotaxin and interleukin-5 in blister fluid of bullous pemphigoid: correlation with tissue eosinophilia.大疱性类天疱疮疱液中嗜酸性粒细胞趋化因子和白细胞介素-5水平升高：与组织嗜酸性粒细胞增多的相关性。

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The Role of Eosinophils in Bullous Pemphigoid: A Developing Model of Eosinophil Pathogenicity in Mucocutaneous Disease.嗜酸性粒细胞在大疱性类天疱疮中的作用：黏膜皮肤疾病中嗜酸性粒细胞致病性的发展模型

Front Med (Lausanne). 2018 Jul 10;5:201. doi: 10.3389/fmed.2018.00201. eCollection 2018.

The Autoimmune Skin Disease Bullous Pemphigoid: The Role of Mast Cells in Autoantibody-Induced Tissue Injury.自身免疫性皮肤病大疱性类天疱疮：肥大细胞在自身抗体诱导的组织损伤中的作用。

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The pathophysiology of bullous pemphigoid.大疱性类天疱疮的病理生理学

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IgE antibodies in sera from patients with bullous pemphigoid are autoantibodies preferentially directed against the 230-kDa epidermal antigen (BP230).大疱性类天疱疮患者血清中的IgE抗体是优先针对230kDa表皮抗原（BP230）的自身抗体。

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Detection of elevated levels of IL-4, IL-6, and IL-10 in blister fluid of bullous pemphigoid.大疱性类天疱疮疱液中白细胞介素-4、白细胞介素-6和白细胞介素-10水平升高的检测

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本文引用的文献

Bullous pemphigoid, an ultrastructural study of the inflammatory response: eosinophil, basophil and mast cell granule changes in multiple biopsies from one patient.大疱性类天疱疮：炎症反应的超微结构研究——来自一名患者多次活检中嗜酸性粒细胞、嗜碱性粒细胞和肥大细胞颗粒的变化

J Invest Dermatol. 1982 Feb;78(2):91-101. doi: 10.1111/1523-1747.ep12505711.

Cellular events leading to blister formation in bullous pemphigoid.导致大疱性类天疱疮中水疱形成的细胞事件。

Br J Dermatol. 1980 Dec;103(6):615-24. doi: 10.1111/j.1365-2133.1980.tb01683.x.

Bullous pemphigoid blister fluid stimulates eosinophil colony formation and activates eosinophils.大疱性类天疱疮水疱液刺激嗜酸性粒细胞集落形成并激活嗜酸性粒细胞。

Clin Exp Immunol. 1982 Dec;50(3):555-62.

Bullous pemphigoid: a cause of peripheral blood eosinophilia.

J Am Acad Dermatol. 1983 May;8(5):648-51. doi: 10.1016/s0190-9622(83)70073-3.

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.从人血中分离单核细胞和粒细胞。通过一次离心分离单核细胞，通过离心和1g沉降相结合的方法分离粒细胞。

Scand J Clin Lab Invest Suppl. 1968;97:77-89.

Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5).人类嗜酸性粒细胞分化因子（白细胞介素5）编码基因的分子克隆、核苷酸序列及表达

Proc Natl Acad Sci U S A. 1987 Oct;84(19):6629-33. doi: 10.1073/pnas.84.19.6629.

Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors.纯化的白细胞介素5支持小鼠嗜酸性粒细胞前体的终末分化和增殖。

J Exp Med. 1988 Jan 1;167(1):43-56. doi: 10.1084/jem.167.1.43.

Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor.高度纯化的小鼠白细胞介素5（IL-5）可刺激嗜酸性粒细胞功能并延长其体外存活时间。IL-5作为一种嗜酸性粒细胞趋化因子。

J Exp Med. 1988 May 1;167(5):1737-42. doi: 10.1084/jem.167.5.1737.

Recombinant human interleukin 5 is a selective activator of human eosinophil function.重组人白细胞介素5是人类嗜酸性粒细胞功能的选择性激活剂。

J Exp Med. 1988 Jan 1;167(1):219-24. doi: 10.1084/jem.167.1.219.

Mediators of inflammation in blister fluids from patients with pemphigus vulgaris and bullous pemphigoid.寻常型天疱疮和大疱性类天疱疮患者水疱液中的炎症介质

Arch Dermatol. 1989 Jul;125(7):925-30.

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