MELNICK J L
Science. 1962 Mar 30;135(3509):1128-30. doi: 10.1126/science.135.3509.1128.
The papilloma, polyoma, and vacuolating agents seem to form a natural group of tumor viruses, for which the name papova virus group is proposed. Members of the group have the following properties: 45 mmicro diameter, deoxyribonucleic acid core, 42 capsomeres, absence of essential lipids, thermal resistance, slow growth cycle with multiplication within the cell nucleus, and tumorigenicity.
乳头瘤病毒、多瘤病毒和空泡化因子似乎构成了一组天然的肿瘤病毒,为此建议将其命名为乳头多瘤病毒组。该组病毒成员具有以下特性:直径45纳米、脱氧核糖核酸核心、42个壳粒、无必需脂质、耐热性、生长周期缓慢且在细胞核内增殖,以及具有致瘤性。