Miller D H, Buchanan N, Barker G, Morrissey S P, Kendall B E, Rudge P, Khamashta M, Hughes G R, McDonald W I
Institute of Neurology, London, UK.
J Neurol. 1992 Oct;239(8):460-4. doi: 10.1007/BF00856812.
Gadolinium (Gd)-DTPA enhanced magnetic resonance imaging (MRI) was performed in 15 systemic lupus erythematosus patients with past (12) or present (3) features suggesting central nervous system (CNS) involvement. Symptomatic Gd-DTPA enhancing lesions were seen in 2 patients, and immunosuppressive treatment was associated with a rapid reversal of enhancement. The pattern of enhancement was different from that usually seen in multiple sclerosis. Gd-DTPA enhanced MRI may sometimes be useful in demonstrating the activity of CNS lupus.
