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[显微图像分析进展与图像细胞术发展趋势]

[Progress in microscopic image analysis and the trend of image cytometry].

作者信息

Ashihara T, Murata S, Urata Y, Konishi E, Itoi H

机构信息

Department of Pathology, Kyoto Prefectural University of Medicine.

出版信息

Nihon Rinsho. 1992 Oct;50(10):2497-504.

PMID:1447822
Abstract

Image cytometry has recently developed prominently based on the digital imaging of cell morphology brought about by great advances in microcomputer hardware and software, electronics etc. This method is characterized by the quantitation of both the amount of intracellular bioactive materials and cell morphology, and is expected to further advance many cell analysis techniques involving automated cytology, chromosome image analysis, automated histopathology, viable cell analysis, 3D image construction, etc. The present use is still minimal, and advances in both hardware and software for cyto-histologic recognition are essentially necessary. Perhaps by the end of this century, more sophisticated and faster machines for automated cyto-histologic analysis will appear, replacing many microscopic techniques of presently subjective observation in the biomedical field.

摘要

基于微型计算机硬件和软件、电子学等方面的巨大进步所带来的细胞形态数字成像技术,图像细胞术近年来得到了显著发展。该方法的特点是能够对细胞内生物活性物质的数量和细胞形态进行定量分析,有望推动许多细胞分析技术的进一步发展,包括自动化细胞学、染色体图像分析、自动化组织病理学、活细胞分析、三维图像构建等。目前其应用仍然有限,细胞组织学识别的硬件和软件方面的进步至关重要。也许到本世纪末,会出现更精密、更快速的自动化细胞组织学分析机器,取代生物医学领域目前许多主观观察的显微镜技术。

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