Hayata I
Division of Radiation Hazards, National Institute of Radiological Sciences.
Nihon Rinsho. 1992 Oct;50(10):2547-52.
This is a review of the development of automated systems of chromosome analysis. The history of its development reflects the progress of image analysis systems and that of method of chromosome analysis in man. It can be chronologically summarized as follows. Period I: 1960s-early 1970s when chromosome banding methods were discovered. Period II: early 1970s-early 1980s when the first image analysis system of chromosome was commercialized. Period III: early 1980s-present. Research and development of the automated analysis system of radiation induced chromosome aberrations, conducted under the national project of cross-over research on underlying technology of nuclear energy, Science and Technology Agency, Japan, is briefly reported.
本文是对染色体分析自动化系统发展历程的综述。其发展历史反映了图像分析系统以及人类染色体分析方法的进步。按时间顺序总结如下:第一阶段:20世纪60年代至70年代初,此时染色体显带方法被发现。第二阶段:20世纪70年代初至80年代初,首个染色体图像分析系统实现商业化。第三阶段:20世纪80年代初至今。简要报道了在日本科学技术厅核能基础技术交叉研究国家项目下开展的辐射诱导染色体畸变自动分析系统的研发情况。