L-丙氨酸脱氢酶：一种控制蜡样芽孢杆菌孢子氨基酸诱导萌发特异性的机制。
L-Alanine dehydrogenase: a mechanism controlling the specificity of amino acid-induced germination of Bacillus cereus spores.
作者信息
O'CONNOR R J, HALVORSON H O
出版信息
J Bacteriol. 1961 Nov;82(5):706-13. doi: 10.1128/jb.82.5.706-713.1961.
Abstract
O'Connor, R. J. (University of Wisconsin, Madison), and Harlyn O. Halvorson. L-Alanine dehydrogenase: A mechanism controlling the specificity of amino acid-induced germination of Bacillus cereus spores. J. Bacteriol. 82:706-713. 1961.-A study has been undertaken of the properties and specificity of germination of spores of Bacillus cereus strain T. In the absence of additional carbon sources, only l-alanine, l-alpha-NH(2)-n-butyric acid, and l-cysteine were effective germinating agents. The physical properties of germination, induced by l-alanine and l-alpha-NH(2)-n-butyric acid following extended heat shock, were in close agreement with those of l-alanine dehydrogenase. The specificity of the germination system, as well as amino acid deamination in vivo, support the view that l-alanine dehydrogenase activity is essential for germination and that the enzyme serves as the initial binding site for l-alanine in heat-shocked spores.
摘要
奥康纳，R. J.（威斯康星大学麦迪逊分校），以及哈林·O. 哈尔沃森。L-丙氨酸脱氢酶：一种控制蜡样芽孢杆菌孢子氨基酸诱导萌发特异性的机制。《细菌学杂志》82:706 - 713。1961年。——对蜡样芽孢杆菌T菌株孢子萌发的特性和特异性进行了研究。在没有额外碳源的情况下，只有L-丙氨酸、L-α-氨基正丁酸和L-半胱氨酸是有效的萌发剂。在长时间热休克后，由L-丙氨酸和L-α-氨基正丁酸诱导的萌发的物理特性与L-丙氨酸脱氢酶的特性密切一致。萌发系统的特异性以及体内氨基酸脱氨作用支持这样一种观点，即L-丙氨酸脱氢酶活性对于萌发至关重要，并且该酶作为热休克孢子中L-丙氨酸的初始结合位点。
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