Asahi Takashi, Tamura Ryoi, Eifuku Satoshi, Hayashi Nakamasa, Endo Shunro, Nishijo Hisao, Ono Taketoshi
Faculty of Medicine, Department of Physiology, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan.
Neurosci Res. 2003 Oct;47(2):255-60. doi: 10.1016/s0168-0102(03)00202-5.
For single-unit recording from the brain in monkeys, the precise determination of recording targets is essential. Although magnetic resonance imaging (MRI) has been used recently in several laboratories, it has been difficult to obtain three-dimensional information on a target from two-dimensional pictures, and, therefore, it has also been difficult to determine precise coordinates. We developed a new method for precisely determining target-area coordinates based on reconstructed rendering pictures made from three-dimensional MRI data. We also combined this method with magnetic resonance angiography to avoid severe vessel complications in recording experiments.
对于在猴子大脑中进行单神经元记录，精确确定记录靶点至关重要。尽管最近几个实验室已使用磁共振成像（MRI），但从二维图像中获取靶点的三维信息一直很困难，因此，精确确定坐标也很困难。我们基于从三维MRI数据重建的渲染图像，开发了一种精确确定靶点区域坐标的新方法。我们还将此方法与磁共振血管造影相结合，以避免在记录实验中出现严重的血管并发症。
