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[一项关于蔬菜抑制抗肿瘤药物致突变性的SOS诱导试验筛选研究]

[A SOS induction test screening study for vegetables inhibiting mutagenicity caused by antineoplastic drugs].

作者信息

Zhao Z Z, Huang M T

机构信息

Hebei Cancer Institute, Shijiazhuang.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 1992 Mar;26(2):92-3.

PMID:1451586
Abstract

Using mutational and anti-mutational synchronous in SOS inductest (+/- S9), We found that 7 out of 11 kinds of commonly eaten vegetables had the ability to inhibit mutagenicity caused by chemical drugs such as Mitomycin C, Bleomycinia, Fluorouracil, Cis-Diaminodichloroplatinum, Arabinosylcytosin and mustargen, They were garlic, green Chinese onion, onion, garlic bulb, tomato, cucumber and water radish. The other 4 lacking this ability were rape, chinese toon, ginger and asparagus lettuce stalk. We believe that our results can be helpful in the preparation. of cancer patients' diet, who are receiving chemotherapy and in the prevention of cancer.

摘要

在SOS诱导试验(±S9)中使用突变和抗突变同步方法,我们发现11种常见食用蔬菜中有7种具有抑制丝裂霉素C、博莱霉素、氟尿嘧啶、顺二氨基二氯铂、阿糖胞苷和氮芥等化学药物致突变性的能力,它们是大蒜、青葱、洋葱、蒜球、番茄、黄瓜和水萝卜。另外4种缺乏这种能力的是油菜、香椿、姜和莴笋茎。我们相信我们的结果有助于正在接受化疗的癌症患者饮食的准备以及癌症的预防。

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