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1999年至2001年蒙大拿州和怀俄明州美国印第安青年糖尿病的三年患病率和发病率

Three-year prevalence and incidence of diabetes among American Indian youth in Montana and Wyoming, 1999 to 2001.

作者信息

Moore Kelly R, Harwell Todd S, McDowall Janet M, Helgerson Steven D, Gohdes Dorothy

机构信息

Billings Area Indian Health Service, Billings, Montana, USA.

出版信息

J Pediatr. 2003 Sep;143(3):368-71. doi: 10.1067/S0022-3476(03)00295-6.

Abstract

OBJECTIVES

To estimate the prevalence and incidence of type 2 diabetes among American Indian youth.

STUDY DESIGN

Medical records were reviewed annually for all patients with diabetes who were <20 years of age at 6 Indian Health Service facilities in Montana and Wyoming. All cases < or =5 years of age or weight per age < or =10th percentile at diagnosis or with islet cell antibodies were considered as probable type 1. Among the remaining cases, probable type 2 diabetes was defined when a child had one or more of the following characteristics: weight per age > or =95th percentile or acanthosis nigricans at diagnosis, elevated C-peptide or insulin, family history of type 2 diabetes; treatment with oral agents with or without insulin or no hypoglycemic therapy after 1 year of follow-up.

RESULTS

From 1999 to 2001, 53% of prevalent cases and 70% of incident cases were categorized as probable type 2 diabetes. The average annual prevalence of probable type 1 and type 2 diabetes was 0.7 and 1.3 per 1000. The average annual incidence rates for probable type 1, and type 2 diabetes were 5.8, 23.3 per 100,000.

CONCLUSIONS

The incidence of probable type 2 diabetes was approximately 4 times higher than type 1 diabetes among American Indian youth in Montana and Wyoming

摘要

目的

评估美国印第安青年中2型糖尿病的患病率和发病率。

研究设计

对蒙大拿州和怀俄明州6家印第安卫生服务机构中所有年龄小于20岁的糖尿病患者的病历进行年度审查。所有年龄小于或等于5岁、诊断时体重低于或等于同年龄第10百分位数或伴有胰岛细胞抗体的病例被视为可能的1型糖尿病。在其余病例中,当儿童具有以下一项或多项特征时,定义为可能的2型糖尿病:诊断时年龄别体重高于或等于第95百分位数或黑棘皮症、C肽或胰岛素升高、2型糖尿病家族史;随访1年后接受口服降糖药治疗(无论是否联用胰岛素)或未接受降糖治疗。

结果

1999年至2001年,53%的现患病例和70%的新发病例被归类为可能的2型糖尿病。可能的1型和2型糖尿病的年平均患病率分别为每1000人中有0.7例和1.3例。可能的1型和2型糖尿病的年平均发病率分别为每10万人中有5.8例和23.3例。

结论

在蒙大拿州和怀俄明州的美国印第安青年中,可能的2型糖尿病发病率约为1型糖尿病的4倍。

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