Konishi Tenji, Yamazoe Kiyonori, Kanzato Masahiro, Konoshima Takao, Fujiwara Yasuhiro
Kyoto Pharmaceutical University, Misasagi, Japan.
Chem Pharm Bull (Tokyo). 2003 Oct;51(10):1142-6. doi: 10.1248/cpb.51.1142.
Three new diterpenoids, excoecarins V1-V3 (1-3) and a new flavanone glycoside (7) were isolated from the fresh stem of Excoecaria agallocha L. Their structures were elucidated as: 2alpha,3alpha,18-trihydroxy-3beta,20-epoxybeyer-15-ene (1), ent-2,3-secokaur-16-en-2,3-dioic acid (2), ent-3,4-seco-16alpha-hydroxyatis-4(19)-en-3-oic acid (3), and 3,5,7,3',5'-pentahydroxy-2R,3R-flavanonol 3-O-alpha-L-rhamnopyranoside (7) on the basis of spectroscopic data, chemical evidence, and/or X-ray analysis.
从海漆新鲜茎中分离出三种新的二萜类化合物，即海漆素V1 - V3（1 - 3）和一种新的黄烷酮糖苷（7）。基于光谱数据、化学证据和/或X射线分析，它们的结构被鉴定为：2α,3α,18 - 三羟基 - 3β,20 - 环氧贝壳杉 - 15 - 烯（1）、对映 - 2,3 - 断贝壳杉 - 16 - 烯 - 2,3 - 二酸（2）、对映 - 3,4 - 断 - 16α - 羟基阿替斯 - 4(19) - 烯 - 3 - 酸（3）以及3,5,7,3',5' - 五羟基 - 2R,3R - 黄烷醇3 - O - α - L - 鼠李糖苷（7）。
