从海漆新鲜茎中提取的三种二萜类化合物（海漆素V1 - V3）和一种黄酮醇苷。

Three diterpenoids (excoecarins V1-V3) and a flavanone glycoside from the fresh stem of Excoecaria agallocha.

作者信息

Konishi Tenji, Yamazoe Kiyonori, Kanzato Masahiro, Konoshima Takao, Fujiwara Yasuhiro

机构信息

Kyoto Pharmaceutical University, Misasagi, Japan.

出版信息

Chem Pharm Bull (Tokyo). 2003 Oct;51(10):1142-6. doi: 10.1248/cpb.51.1142.

DOI:10.1248/cpb.51.1142

PMID:14519918

Abstract

Three new diterpenoids, excoecarins V1-V3 (1-3) and a new flavanone glycoside (7) were isolated from the fresh stem of Excoecaria agallocha L. Their structures were elucidated as: 2alpha,3alpha,18-trihydroxy-3beta,20-epoxybeyer-15-ene (1), ent-2,3-secokaur-16-en-2,3-dioic acid (2), ent-3,4-seco-16alpha-hydroxyatis-4(19)-en-3-oic acid (3), and 3,5,7,3',5'-pentahydroxy-2R,3R-flavanonol 3-O-alpha-L-rhamnopyranoside (7) on the basis of spectroscopic data, chemical evidence, and/or X-ray analysis.

摘要

从海漆新鲜茎中分离出三种新的二萜类化合物，即海漆素V1 - V3（1 - 3）和一种新的黄烷酮糖苷（7）。基于光谱数据、化学证据和/或X射线分析，它们的结构被鉴定为：2α,3α,18 - 三羟基 - 3β,20 - 环氧贝壳杉 - 15 - 烯（1）、对映 - 2,3 - 断贝壳杉 - 16 - 烯 - 2,3 - 二酸（2）、对映 - 3,4 - 断 - 16α - 羟基阿替斯 - 4(19) - 烯 - 3 - 酸（3）以及3,5,7,3',5' - 五羟基 - 2R,3R - 黄烷醇3 - O - α - L - 鼠李糖苷（7）。