Polkinghorne P J, Uliss A I, Hamilton A M
Moorfields Eye Hospital, London, UK.
Int Ophthalmol. 1992 May;16(3):133-7. doi: 10.1007/BF00916431.
Thirteen young diabetic patients with peripheral capillary non perfusion who presented with symptoms of mild maculopathy were reviewed retrospectively. In this group, peripheral retinal ischaemia was often overlooked and a rapidly progressive proliferative retinopathy developed. Fluorescein angiography of the peripheral retina showed capillary closure, but with preservation of arterioles and venules. In this series, half of the eyes lost vision. In seven eyes where the peripheral ischaemia was treated by pan retinal photocoagulation, the maculopathy resolved without any specific laser treatment to the macula. In young diabetics presenting with maculopathy, the peripheral retina should be examined for ischaemia, and if present, pan retinal laser photocoagulation should be performed. Focal treatment for the macular disease can be delayed until after the peripheral photocoagulation, as the maculopathy may remit.
对13例患有外周毛细血管无灌注且伴有轻度黄斑病变症状的年轻糖尿病患者进行了回顾性研究。在该组中,周边视网膜缺血常被忽视,进而发展为快速进展的增殖性视网膜病变。周边视网膜荧光血管造影显示毛细血管闭塞,但小动脉和小静脉保留。在该系列研究中,半数患眼视力丧失。在7只通过全视网膜光凝治疗周边缺血的患眼中,黄斑病变未经任何针对黄斑的特殊激光治疗即得到缓解。对于出现黄斑病变的年轻糖尿病患者,应检查周边视网膜是否存在缺血,若存在缺血,则应进行全视网膜激光光凝治疗。黄斑疾病的局部治疗可推迟至周边光凝治疗之后,因为黄斑病变可能会自行缓解。