Koch G
The Institute for Postgraduate Dental Education, Jönköping, Sweden.
Eur J Paediatr Dent. 2003 Sep;4(3):127-8.
This was to study the prevalence of dental fluorosis in a Swedish city (Uppsala) with natural 1-1.2 ppm F in drinking water. It was also to compare the prevalence of idiopathic enamel disturbances (Morbus S) in children born in Uppsala with the prevalence in children who had moved in to Uppsala at an age when the Uppsala water could not have influenced the development of Morbus S.
Children born in 1970 and 1967 in Uppsala (Sweden) on even days (n=840) were invited to the study. All children not born in Uppsala were included (n=475), 24 children refused to take part and 45 were sick or had moved. Four examination teams performed the examinations after calibration against a "gold standard". Dental fluorosis was determined by the criteria of Dean [1934], idiopathic white spots according to Nevitt et al. [1963] and Morbus S was diagnosed according to Forsman [1979].
Children born in Uppsala had a higher prevalence and severity of fluorosis compared with those not born in Uppsala. It was found that 40 out of the 715 children born in Uppsala had enamel disturbances according to criteria for Morbus S and the corresponding figures for children not born in Uppsala were 33 out of 486.
The specific enamel hypomineralisations type Morbus S cannot be connected to intake of fluoride.
本研究旨在调查瑞典乌普萨拉市饮用水中天然氟含量为1 - 1.2 ppm时氟斑牙的患病率。同时,比较在乌普萨拉出生的儿童与在能受乌普萨拉市水源影响而出现特发性釉质发育异常(莫尔布斯S型)的年龄时迁入该市的儿童中特发性釉质发育异常的患病率。
邀请1970年和1967年在瑞典乌普萨拉市偶数日出生的儿童(n = 840)参与研究。纳入所有非乌普萨拉市出生的儿童(n = 475),24名儿童拒绝参与,45名儿童生病或已搬家。四个检查小组在参照“金标准”校准后进行检查。根据Dean[1934]的标准确定氟斑牙,根据Nevitt等人[1963]的标准确定特发性白斑,根据Forsman[1979]的标准诊断莫尔布斯S型。
与非乌普萨拉市出生的儿童相比,乌普萨拉市出生的儿童氟斑牙的患病率和严重程度更高。研究发现,715名乌普萨拉市出生的儿童中有40名根据莫尔布斯S型标准存在釉质发育异常,非乌普萨拉市出生的儿童中相应数字为486名中有33名。
莫尔布斯S型特定的釉质矿化不全与氟摄入无关。