Briggs Nathaniel C, Levine Robert S, Hall H Irene, Cosby Otis, Brann Edward A, Hennekens Charles H
Department of Internal Medicine, Meharry Medical College, Nashville, TN 37208, USA.
Am J Public Health. 2003 Oct;93(10):1748-52. doi: 10.2105/ajph.93.10.1748.
This study examined occupational risks for non-Hodgkin's lymphoma, Hodgkin's disease, and soft-tissue sarcoma among African American and White men.
Race-specific multivariate logistic regression analyses were conducted using data from a large US population-based case-control study.
Significant occupational risks were limited to African Americans; chromium was associated with non-Hodgkin's lymphoma (odds ratio [OR] = 3.9, 95% confidence interval [CI] = 1.2, 12.9) and wood dust was associated with Hodgkin's disease (OR = 4.6, 95% CI = 1.6, 13.3) and soft-tissue sarcoma (OR = 3.7, 95% CI = 1.6, 8.6).
Race-specific occupational risk factors for cancer were evident only among African American men. This may reflect racial disparities in levels of exposure to occupational carcinogens.
本研究调查了非裔美国男性和白人男性患非霍奇金淋巴瘤、霍奇金病和软组织肉瘤的职业风险。
使用来自一项基于美国大规模人群的病例对照研究的数据进行种族特异性多因素逻辑回归分析。
显著的职业风险仅限于非裔美国人；铬与非霍奇金淋巴瘤相关（比值比[OR]=3.9，95%置信区间[CI]=1.2，12.9），木尘与霍奇金病相关（OR=4.6，95%CI=1.6，13.3）以及软组织肉瘤相关（OR=3.7，95%CI=1.6，8.6）。
种族特异性的癌症职业风险因素仅在非裔美国男性中明显。这可能反映了职业致癌物暴露水平的种族差异。
