Korkuschko O W, Kotko D N
Aktuelle Gerontol. 1976 Jun;6(6):305-10.
For understanding age peculiarities of gastric secretory function in aging.tory function in aging.tory function regulation, the investigation of nervous influences on gastric secretion is of importance. With this end in view the unconditioned reflex stimulus- the tube with rubber balloon, containing 10 ml of water and conditioned reflex stimulus - food stimulus were employed. The fractional gastric intubation was carried out. The gastric secretion in response to mechanical stimulus was investigated in 125 persons aged 60-89 and in 40 persons aged 20-25 (control group). In response to conditioned reflex stimulus it was studied in 30 persons aged 60-89 and 10 persons aged 20-35 (control group). With aging the response of gastric glands to unconditioned and conditioned stimuli was found to decrease. The amount of secretion, hydrochloric acid, pepsin, and gastromuco-protein were decreased, the secretory effect being more slowly developed, the torpid secretion type being observed. The above facts testify to changes of nervous regulation of gastric secre
为了解衰老过程中胃分泌功能的年龄特点及分泌功能调节，研究神经对胃分泌的影响具有重要意义。为此，采用了非条件反射刺激——装有10毫升水的带橡胶气球的管子，以及条件反射刺激——食物刺激。进行了分段胃插管。对125名60 - 89岁的人和40名20 - 25岁的人（对照组）进行了机械刺激引起的胃分泌研究。对30名60 - 89岁的人和10名20 - 35岁的人（对照组）进行了条件反射刺激引起的胃分泌研究。随着年龄增长，发现胃腺对非条件和条件刺激的反应降低。分泌量、盐酸、胃蛋白酶和胃黏液蛋白减少，分泌效应发展更缓慢，观察到迟缓分泌型。上述事实证明胃分泌神经调节发生了变化
