Zarzycki W, Badurski J, Jaworowska E, Sarosiek J
Dtsch Z Verdau Stoffwechselkr. 1986;46(4):209-16.
The aim of the thesis was the observation of the gastric mucus secretion on the basis of carbohydrate components and protein secretion into the gastric lumen. 15 healthy volunteers were investigated: 7 males and 8 females aged 20-37 (average rate 27). In this group gastric juice was aspirated after administration of single 6 micrograms/kg BW stimulus of pentagastrin. Concentration and output of hydrochloric acid, pepsin, protein and carbohydrate components of gastric juice fucose, sialic acid, hexosamines and hexoses were measured. Carbohydrate components and proteins included informations concerning gastric mucus secretion into gastric lumen. It was shown that the highest gastric mucus secretion occurred before maximal gastric acid secretion. This is of importance for keeping balance between so called aggressive and protective mechanisms. It is of great importance in pathophysiology of stomach.
本论文的目的是基于碳水化合物成分观察胃黏液分泌以及蛋白质向胃腔的分泌情况。对15名健康志愿者进行了研究：7名男性和8名女性，年龄在20 - 37岁之间（平均年龄27岁）。在该组中，给予单次6微克/千克体重的五肽胃泌素刺激后抽吸胃液。测量了胃液中盐酸、胃蛋白酶、蛋白质以及碳水化合物成分岩藻糖、唾液酸、己糖胺和己糖的浓度及分泌量。碳水化合物成分和蛋白质包含了有关胃黏液向胃腔分泌的信息。结果表明，最高的胃黏液分泌发生在胃酸分泌达到最大值之前。这对于维持所谓的攻击和保护机制之间的平衡很重要。它在胃的病理生理学中具有重要意义。
