Friedlander Arthur H, Yagiela John A, Paterno Victoria I, Mahler Michael E
VA Greater Los Angeles Healthcare System, and Hospital Dental Service, UCLA Medical Center, CA 90073, USA.
J Calif Dent Assoc. 2003 Sep;31(9):681-2, 684, 686-91.
Autism is a lifelong, severe, developmental disorder that appears initially in infancy and early childhood and impairs the acquisition of some of the most important skills in human life. The disease is characterized by impaired social interactions, verbal and nonverbal communication deficiencies, limited activities and interest, and repetitive behaviors. Often accompanying the disorder are behavioral disturbances, such as self-mutilation and aggression, psychiatric symptoms, and seizures, which necessitate the administration of multiple medications to help the affected individual participate effectively in the educational and rehabilitative process. Dentists caring for these people must be familiar with the manifestations of the disease and its associated features so that they can garner the maximum level of cooperation. They must also be familiar with the medications used to treat the associated features of the disorder because many of these pharmaceuticals cause untoward orofacial and systemic reactions and may precipitate adverse interactions with dental therapeutic agents.
自闭症是一种终身的、严重的发育障碍，最初出现在婴儿期和幼儿期，会损害人类生活中一些最重要技能的习得。该疾病的特征是社交互动受损、言语和非言语沟通缺陷、活动和兴趣有限以及重复行为。这种障碍常常伴有行为紊乱，如自残和攻击行为、精神症状以及癫痫发作，这就需要使用多种药物来帮助患者有效地参与教育和康复过程。照顾这些患者的牙医必须熟悉该疾病的表现及其相关特征，以便能够获得最大程度的合作。他们还必须熟悉用于治疗该障碍相关特征的药物，因为这些药物中的许多会引起不良的口腔面部和全身反应，并且可能与牙科治疗药物产生不良相互作用。
