Friedlander Arthur H, Yagiela John A, Paterno Victoria I, Mahler Michael E
VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd., Los Angeles, CA 90073, USA.
J Am Dent Assoc. 2006 Nov;137(11):1517-27. doi: 10.14219/jada.archive.2006.0086.
A paucity of information exists in the dental literature about autism and its dental implications.
The authors conducted a MEDLINE search for the period 2000 through 2006, using the term "autism," with the aim of defining the condition's clinical manifestations, dental and medical treatment and dental implications.
Autism is a severe developmental brain disorder that appears in infancy, persists throughout life, and is characterized by impaired social interaction, abnormalities in communication (both verbal and nonverbal) and restricted interests. Often accompanying the disorder are behavioral disturbances - such as self-mutilation, aggression, psychiatric symptoms and seizures - that necessitate the administration of multiple medications to help the affected person participate effectively in the educational and rehabilitative process.
Dentists caring for people with autism must be familiar with the manifestations of the disease and its associated features so that they can garner the maximum level of patient cooperation. They also must be familiar with the medications used to treat the associated features of the disorder because many of them cause untoward orofacial and systemic reactions and may precipitate adverse interactions with dental therapeutic agents.
牙科文献中关于自闭症及其牙科影响的信息匮乏。
作者对2000年至2006年期间进行了MEDLINE检索，使用“自闭症”一词，旨在界定该病症的临床表现、牙科和医学治疗以及牙科影响。
自闭症是一种严重的发育性脑部疾病，出现在婴儿期，终生存在，其特征为社交互动受损、沟通异常（包括言语和非言语沟通）以及兴趣受限。该病症常伴有行为障碍，如自残、攻击行为、精神症状和癫痫发作，这需要使用多种药物来帮助患者有效参与教育和康复过程。
照顾自闭症患者的牙医必须熟悉该疾病的表现及其相关特征，以便获得患者的最大程度配合。他们还必须熟悉用于治疗该病症相关特征的药物，因为其中许多药物会引起不良的口腔面部和全身反应，并且可能与牙科治疗药物产生不良相互作用。
