Li Lihua, Ding Shan, Zhou Changren
Biomaterials Research Lab, Chemistry Department, Jinan University, Guangzhou 510630.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2003 Sep;20(3):398-400.
Hypersusceptibility test, pyrogen test, cell cultivation, and toxicity examination were applied in the biological evaluation of the poly(lactic acid) (PLA)/chitosan composite materials. The results indicated that all the materials were negative, conforming to the ISO10993-1. The cell could grow well on the surface of the materials. So the PLA/chitosan composite materials have good biocompatibility and can be planted in the body as scaffolds.
采用过敏试验、热原试验、细胞培养和毒性检查对聚乳酸（PLA）/壳聚糖复合材料进行生物学评价。结果表明，所有材料均为阴性，符合ISO10993-1标准。细胞能够在材料表面良好生长。因此，PLA/壳聚糖复合材料具有良好的生物相容性，可作为支架植入体内。
