Dahhaoui M, Lannou J, Stelz T, Caston J, Guastavino J M
Laboratoire de Neurophysiologie sensorielle, Faculté des Sciences de Rouen, Mont-Saint-Aignan, France.
Behav Neural Biol. 1992 Nov;58(3):180-9. doi: 10.1016/0163-1047(92)90440-f.
Adult DA/HAN strain rats were submitted to a spatial orientation task consisting of finding a reward in an open field. They were first submitted to an initial learning session and 10 days later to a retrieval test. The animals were divided into four groups of five rats each: animals that were cerebellectomized before the initial learning session or after the initial learning session, sham-operated rats, and control (intact) animals. Different parameters that characterize the spatiotemporal organization of the rat's exploratory behavior were quantified. From the results, it can be concluded that the cerebellum is not absolutely necessary in the processes that sustain spatial learning but that it is involved in the mechanisms sustaining focused spatial memory and in the cognitive processes of the motor program elaboration and not only in the regulation of the movement being done.
成年DA/HAN品系大鼠接受了一项空间定向任务，即在开放场地中寻找奖励。它们首先接受初始学习阶段，10天后进行检索测试。动物被分为四组，每组五只大鼠：在初始学习阶段之前或之后进行小脑切除的动物、假手术大鼠和对照（完整）动物。对表征大鼠探索行为时空组织的不同参数进行了量化。从结果可以得出结论，小脑在维持空间学习的过程中并非绝对必要，但它参与了维持集中空间记忆的机制以及运动程序制定的认知过程，而不仅仅是参与正在进行的运动的调节。
