Nakamura Charles E, Whited Gregory M
DuPont Central Research & Development Experimental Station, 328/245A Wilmington, DE 19880-0328, USA.
Curr Opin Biotechnol. 2003 Oct;14(5):454-9. doi: 10.1016/j.copbio.2003.08.005.
Improvements in the biological production of 1,3-propanediol, a key component of an emerging polymer business, have been realized. Utilizing genes from natural strains that produce 1,3-propanediol from glycerol, metabolic engineering has enabled the development of a recombinant strain that utilizes the lower cost feedstock D-glucose. This accomplishment bodes well for future metabolic engineering efforts and, ultimately, for increased societal benefit obtained through the production of chemicals from renewable resources.
新兴聚合物业务的关键成分1,3 - 丙二醇的生物生产已取得进展。利用从能将甘油转化为1,3 - 丙二醇的天然菌株中获取的基因，代谢工程已培育出一种能利用成本更低的原料D - 葡萄糖的重组菌株。这一成果对于未来的代谢工程研究而言是个好兆头，最终也有利于通过利用可再生资源生产化学品为社会带来更多益处。
