Marren P, De Berker D, Millard P, Wojnarowska F
Department of Dermatology, John Radcliffe Hospital, Oxford, UK.
Clin Exp Dermatol. 1992 Sep;17(5):354-6. doi: 10.1111/j.1365-2230.1992.tb00231.x.
We describe a patient who developed a generalized blistering eruption due to lichen sclerosus and who was observed to have scalp involvement. Both are unusual manifestations of this disease which merit consideration. Lichen sclerosus is an uncommon disease that most frequently affects the external genitalia of perimenopausal women. The aetiology is unknown. Approximately 20% of affected patients have extragenital lesions that present as small, ivory, shiny round macules or papules that later become atrophic; extragenital lesions are generally asymptomatic. Bullous and haemorrhagic forms may occur but these are generally localized and reports of extensive or generalized involvement are rare. We describe an elderly woman with generalized bullous lichen sclerosus. As an incidental finding, she was observed to have lichen sclerosus affecting her scalp. This has rarely been described and it would appear that she is the third reported case of scalp involvement.
我们描述了一名因硬化性苔藓而出现全身性水疱性皮疹且伴有头皮受累的患者。这两种情况均为此病的不寻常表现，值得关注。硬化性苔藓是一种罕见疾病，最常累及围绝经期女性的外生殖器。病因不明。约20%的受累患者有生殖器外病变，表现为小的、象牙色、有光泽的圆形斑疹或丘疹，随后会萎缩；生殖器外病变通常无症状。大疱性和出血性形式可能会出现，但通常为局限性，广泛或全身性受累的报道很少。我们描述了一名患有全身性大疱性硬化性苔藓的老年女性。作为一个偶然发现，观察到她的头皮也有硬化性苔藓。这很少被描述过，她似乎是第三例有头皮受累报道的病例。
