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阿根廷流产牛胎儿对感染因子的体液免疫反应。

Humoral immune response to infectious agents in aborted bovine fetuses in Argentina.

作者信息

Moore D P, Campero C M, Odeón A C, Bardón J C, Silva-Paulo P, Paolicchi F A, Cipolla A L

机构信息

Instituto Nacional de Tecnología Agropecuaria (INTA), CC 276, 7620 Balcarce, Argentina.

出版信息

Rev Argent Microbiol. 2003 Jul-Sep;35(3):143-8.

PMID:14587376
Abstract

The purpose of this study was to characterize the exposure of bovine aborted fetuses from beef and dairy herds of the humid pampas of Argentina to different infectious agents by the evaluation of fetal fluid antibodies. Presence of fetal antibodies to bovine viral diarrhea virus genotype 1 (BVDV-1), bovine herpes virus type 1 (BHV-1), Leptospira interrogans, Brucella abortus, and Neospora caninum was determined. Of the 95 fetuses processed, 66 came from 49 beef herds and 29 from 12 dairy herds. The average gestational age of the aborted fetuses was 7.1 months. Antibodies to the mentioned agents were detected in 65 of the 95 fetal fluids (68.4%). In addition, antibodies to more than one infectious agent were detected in 32 fetuses (33.7%), suggesting fetal exposure to multiple antigens during gestation. There were antibodies to BVDV-1, BHV-1, N. caninum and Leptospira interrogans in 43 (45.2%), 29 (30.5%), 26 (27.4%) and 5 (5.2%) specimens, respectively. Antibodies to B. abortus were not detected in any of the fetal fluids. The results of this study provide information on the determination of antibodies in fluids from bovine aborted fetuses exposed to different infectious agents in the region.

摘要

本研究的目的是通过评估胎液抗体来表征阿根廷湿润潘帕斯草原肉牛和奶牛群中牛流产胎儿接触不同传染原的情况。测定了胎儿对牛病毒性腹泻病毒1型(BVDV-1)、牛疱疹病毒1型(BHV-1)、问号钩端螺旋体、牛布鲁氏菌和犬新孢子虫的抗体。在处理的95例胎儿中,66例来自49个肉牛群,29例来自12个奶牛群。流产胎儿的平均妊娠年龄为7.1个月。在95份胎液中的65份(68.4%)检测到了针对上述传染原的抗体。此外,在32例胎儿(33.7%)中检测到了针对一种以上传染原的抗体,这表明胎儿在妊娠期接触了多种抗原。分别在43份(45.2%)、29份(30.5%)、26份(27.4%)和5份(5.2%)样本中检测到了针对BVDV-1、BHV-1、犬新孢子虫和问号钩端螺旋体的抗体。在任何一份胎液中均未检测到针对牛布鲁氏菌的抗体。本研究结果为该地区接触不同传染原的牛流产胎儿的胎液中抗体的测定提供了信息。

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