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LDA——一款基于Java的连锁不平衡分析工具。

LDA--a java-based linkage disequilibrium analyzer.

作者信息

Ding Keyue, Zhou Kaixin, He Fuchu, Shen Yan

机构信息

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (and Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing, 100005, People's Republic of China.

出版信息

Bioinformatics. 2003 Nov 1;19(16):2147-8. doi: 10.1093/bioinformatics/btg276.

Abstract

UNLABELLED

We describe an integrated java-based program that provides elaborate graphic and plain-text output of pairwise linkage disequilibrium (LD) analysis of single nucleotide polymorphisms genotypic data. It is most suitable for molecular geneticists, who are focusing on LD measures estimation, statistical significance test and extent prediction.

AVAILABILITY

The software is available at: http://www.chgb.org.cn/lda/lda.htm.

SUPPLEMENTARY INFORMATION

Detailed tutorials, LDA help system and examples are distributed within LDA software. For Macintosh OS X user, the Jre version 1.4 can be downloaded from http://connect.apple.com.

摘要

未标注

我们描述了一个基于Java的集成程序,该程序可提供单核苷酸多态性基因型数据的成对连锁不平衡(LD)分析的详细图形和纯文本输出。它最适合专注于LD测量估计、统计显著性检验和范围预测的分子遗传学家。

可用性

该软件可在以下网址获得:http://www.chgb.org.cn/lda/lda.htm。

补充信息

详细的教程、LDA帮助系统和示例包含在LDA软件中。对于Macintosh OS X用户,可从http://connect.apple.com下载Jre 1.4版本。

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